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Parasız Görüntü...60C5A<br /><a href="https://referanskodunedir.com.tr/bitcoin-nasil-para-kazanilir/" rel="nofollow">Bitcoin Nasıl Para Kazanılır</a><br /><a href="https://dostca.com/" rel="nofollow">Parasız Görüntülü Sohbet</a><br /><a href="https://dostca.com/youtube-abone-satin-al/" rel="nofollow">Youtube Abone Satın Al</a><br /><a href="https://titandijital.com.tr/bee-coin-hangi-borsada/" rel="nofollow">Bee Coin Hangi Borsada</a><br /><a href="https://titandijital.com.tr/cate-coin-hangi-borsada/" rel="nofollow">Cate Coin Hangi Borsada</a><br /><a href="https://dostca.com/spotify-takipci-satin-al/" rel="nofollow">Spotify Takipçi Satın Al</a><br /><a href="https://dostca.com/tiktok-takipci-hilesi/" rel="nofollow">Tiktok Takipçi Hilesi</a><br /><a href="https://referanskodunedir.com.tr/bitcoin-nasil-cikarilir/" rel="nofollow">Bitcoin Nasıl Çıkarılır</a><br /><a href="https://dostca.com/snapchat-takipci-hilesi/" rel="nofollow">Snapchat Takipçi Hilesi</a><br />44BF9Jazmin214B0noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-4412228953305910392019-01-28T15:36:46.383+01:002019-01-28T15:36:46.383+01:00The most important question is who does genetic te...The most important question is who does genetic testing. This blog explain the importance of genetic testing and how it helps. ThanksWho Does Genetic Testinghttps://originalgene.com/about-usnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-27331019598350576672019-01-18T10:30:15.014+01:002019-01-18T10:30:15.014+01:00Thanks for sharing...Thanks for sharing...Dr. Mikehttps://www.localvet.com.au/vet2pet/noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-28978457433836460742018-11-30T06:41:49.724+01:002018-11-30T06:41:49.724+01:00Very nice article... This blog clearly shows the i...Very nice article... This blog clearly shows the importance of gene test to detect gene that causes heart disease. Thanks for sharing<br />Gene that causes heart diseasehttps://originalgene.com/dna-tests/cardio-genetic-testingnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-59292192227862848322018-09-26T21:12:19.427+02:002018-09-26T21:12:19.427+02:00Greetings! Lot of information within this post! It...Greetings! Lot of information within this post! It is the little changes that produce the most significant changes. I found very important information on human genome testing. Thanks for sharing!<br />Human Genome Testinghttps://originalgene.com/glossarynoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-74374357427671359782017-02-05T06:59:34.322+01:002017-02-05T06:59:34.322+01:00A very interesting read having just taken a Family...A very interesting read having just taken a FamilyTreeDNA Family Finder DNA test which covers 3 out of the 6 coeliac genetic markers. However, reading the last response I find it, well, sad really doesn't express it properly, but that a parent wouldn't have a 4yo child not tested simply because it involves a 'biopsy'. Given that this is considered the 'Gold Standard' by which CD is properly diagnosed (although I have a cousins whose 2 biopsy's have been negative but genetic and blood tests both positive), the child will continue to live her life with a 'I'm on a GF diet because my mum says I should be and it hurts if I eat gluten' and will, most likely, get tagged as she gets older with simply being on a fad diet!<br /><br />Biopsy's are not the evil many people seem to believe they are. Yes, it involves some surgery which, like everything we do every single day has risk, but the risk surely outweighs, by far, the consequences of having a proper diagnosis. <br /><br />I wasn't diagnosed until I was 37 and have had 2 further biopsy's in the intervening years because of other issues. My symptoms didn't appear until 6 months before the first biopsy so I was lucky that I made the decision to have it. But, I would be extremely upset (to use a mild word) if I had discovered that my mother had decided, when I was aged 4, to not have a biopsy because of HER beliefs, which could potentially have found the truth at an early age.<br /><br />I was told when I had the first biopsy that now that CD had been diagnosed there would be, in all likelihood, secondary allergies that had been masked by the CD and to expect these to show (which did happen - allergies to amines being the predominant one) but the biopsy did not hurt, I can't even remember it (unlike some of the tests I did have to go through back in the 80's) and it turned my life around from the hell it was before I was diagnosed. Now my DNA test has, on the three markers contained within FTDNA's results, helped show and confirm what I already knew.<br /><br />Good article and good read.Stephen Rowehttp://ser.id.aunoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-74707222020453017202015-10-18T17:16:26.290+02:002015-10-18T17:16:26.290+02:00Thanks for this article. I truly hope more of the...Thanks for this article. I truly hope more of the genetic interpretation sites add in more of the celiac markers. We are pretty concerned that our daughter has Celiac and she does have some major genetic markers but it's difficult to get a confirmation since I keep her off gluten. She had some once recently and she spiked a 105 fever within hours and had abdominal pain. Seemed more severe than typical intolerance. Don't really want to reintroduce it to get a diagnosis, though, and not sending my 4yo in for biopsy. Dr Sarah Stronghttps://www.blogger.com/profile/16270386481476376546noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-68010121511875266052014-05-21T00:46:26.049+02:002014-05-21T00:46:26.049+02:00This was a really interesting read. One of my best...This was a really interesting read. One of my best friends had celiac disease. She was very paranoid about eating gluten, but I understood that she was trying to eat safe. She would get really sick if she accidentally ate something with it. She passed away a year ago from other health issues, but whenever I see gluten-free food at the grocery store it reminds me of her!<br />Claudia Rosenburg | <a href="http://www.rapidmedicalresearch.com/study-77-Celiac-Disease-" rel="nofollow"> http://www.rapidmedicalresearch.com/study-77-Celiac-Disease-</a>Anonymoushttps://www.blogger.com/profile/08528618579653814208noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-12670109030303775062014-04-14T19:52:31.816+02:002014-04-14T19:52:31.816+02:00I once went to a clinical trial for celiac disease...I once went to a clinical trial for celiac disease. I'm so glad that I did because ever since, I've gotten my eating habits underway and controlled. I don't feel sick often anymore. http://www.rapidmedicalresearch.com/study-77-Celiac-Disease- Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-86451081645299640772014-03-06T07:36:34.472+01:002014-03-06T07:36:34.472+01:00Nice article Keith. Assessment should be done with...Nice article Keith. Assessment should be done with all care and seriousness. Even one percent of unseen consequences can put the life of the patient in utmost danger. Doctors and all medical staffs should do risk assessments with all their hearts.<br /><br />Health And Safety Risk Assessmenthttp://conservosafety.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-28805684680208533592013-06-17T04:04:37.742+02:002013-06-17T04:04:37.742+02:00Enterolab does genome testing for CD and non-celia...Enterolab does genome testing for CD and non-celiac gluten sensitivity. Something like $169 including FedEx shipping. They don't test for HLA-DQA.<br /><br />Gluten Free Society also does genome testing for CD and non-celiac gluten sensitivity. They test for both HLA-DQA and HLA-DQB for something like $350.<br /><br />In v3 23andMe tests for 5 of the 6 SNPs referenced in the Monsuur et. al article you cite above. DQ 2.5 = rs2187668 (T). DQ7 = rs4639334 (A). DQ8 = rs7454108 (G). DQ 2.2 requires a test of 3 genes, two for inclusion, rs2395182 (T) and rs7775228 (C). The third one, that would exclude a person from being DQ 2.2 and make them DQ 4 instead, is to not be rs4713586(C). 23andMe does not test for the last one. Someone meeting all three criteria for DQ 2.2 has genoset 221.Lynn M.https://www.blogger.com/profile/04108435081445060650noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-58787913742506291272011-06-14T11:51:24.736+02:002011-06-14T11:51:24.736+02:00Thanks Elaine - that's a very good point about...Thanks Elaine - that's a very good point about a potential negative aspect of breastfeeding - it makes it all the more important that any information used to formulate advice must be thoroughly researched.Keith Grimaldihttp://eurogene.blogspot.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-85447501280666328352011-06-13T22:18:22.876+02:002011-06-13T22:18:22.876+02:00Breastfeeding is indeed a very emotive subject, an...Breastfeeding is indeed a very emotive subject, and IQ is only one of the claimed benefits. It has also been studied with respect to obesity, eczema, chest/ear infections, plus benefits for mother (lowers risk breast/ovarian cancer). <br /><br />Each individual genotype will have some beneficial variants and some less so and untangling each contribution may not be worth much.<br /><br />Also, it is risky to make mothers feel guilty for not being able to breastfeed - postnatal depression is worse for mother and baby than formula milk.Elaine Westwickhttp://www.elainewestwick.blogspot.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-30488184990103298782011-02-03T13:32:02.528+01:002011-02-03T13:32:02.528+01:00@Anon
I would not define Genewize as a scam or a ...@Anon<br /><br />I would not define Genewize as a scam or a fraud without knowing more about it - it's a serious accusation to make, especially at a congress hearing. I am quite sure that Kutz does not know all the details - just like they made false accusations back in 2006.<br /><br />However - is it a scam or is it worthwhile, that is the question you need to know. Genwize/Genelink have been around for a long time. The SNPs that they have in their profiles are reasonable, there are gene-diet interactions that have been demonstrated and they do provide a bibliography. The real problem that I have is that the main business is to sell supplements. While there is nothing inherently wrong with that, the Genewize website does not give much information - yes it gives some ingredients, says they are proven, and so on BUT they do not provide the bibliography that connects SNP to supplement to positive effect. They are fairly transparent regarding the genetics but far too opaque regarding the supplements - so the question remains open, it's one you should ask them and expect a satisfactory answer to before engaging in their business.Keith Grimaldihttp://eurogene.blogspot.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-24095623835443317902011-02-03T12:44:07.678+01:002011-02-03T12:44:07.678+01:00Hi Keith,
I was approached about joining GeneWize...Hi Keith,<br /><br />I was approached about joining GeneWize. I googled GeneWize "scam" "ripoff" "fraud" and came up with much fewer results than I would have expected for multi-level marketing. I'm tempted but it still doesn't feel right. If you're comfortable, can you explain to me whether GeneWize is a fraud or are they being unjustly accused of being fraudulent? If they are a fraud is it because their science is faulty or because their business practices are shady, or both? Thanks!Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-8264027609927019522011-01-21T22:00:08.769+01:002011-01-21T22:00:08.769+01:00It will be interesting to see the results from the...It will be interesting to see the results from these trials in due course. It's good to see that some proper studies are being done.<br /><br />There's an extensive thread on coeliac disease in the 23andMe Forums which you might find of interest:<br /><br />https://www.23andme.com/you/community/thread/460<br /><br />23andMe have said they will begin loading data today and over the next few days. They apparently have "many thousands of data-sets to load". You should start getting results soon. It will be interesting to know what extras you get with the new chip. I held off upgrading. I'm not too sure that I want to sign up for a subscription and also I would have had to pay the expensive courier charges to send them a new DNA sample. I don't know why they can't use ordinary post like everyone else!Debbie Kennetthttps://www.blogger.com/profile/11573470282571579765noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-2863662520544745112011-01-21T18:59:25.100+01:002011-01-21T18:59:25.100+01:00Thanks Debbie - the EAT trial looks interesting. T...Thanks Debbie - the EAT trial looks interesting. The PreventCD trial is looking at adding small amounts of gluten during months 4-6, while still breast feeding and as the project implies, it is focussed on Coeliac disease rather than general allergies. There is also another clinical trial where they are looking at adding gluten at 6 or 12 months (don't know what evidence they used to select those time periods though).<br /><br />The 23andMe panel doesn't unfortunately allow you to determine whether you are HLA DQ2 or DQ8 which are the genotypes necessary for developing celiac - unless they have added extra tagging SNPs for the upgrade...I'm still waiting for my results!Keith Grimaldihttp://eurogene.blogspot.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-88530267870639132032011-01-21T18:40:19.106+01:002011-01-21T18:40:19.106+01:00Many thanks for an interesting blog post. It was u...Many thanks for an interesting blog post. It was unfortunate that the BMJ article, which offered no new evidence and quoted very selectively from the literature, was featured on the front page of so many newspapers and in some cases with very misleading headlines.<br /><br />There is an interesting new study which was mentioned in The Times the other day which might eventually help to provide some answers. The article is behind The Times paywall:<br /><br />http://www.thetimes.co.uk/tto/health/child-health/article2877749.ece<br /><br />This new study is from an organisation called Eating about Tolerance and there is further information on their website:<br /><br />http://www.eatstudy.co.uk<br /><br />The 23andMe test already includes four SNPs associated with coeliac disease. I have the low-risk version of the one that is supposedly the most problematic. I am sure that the day will come when parents will be able to use results from genetic tests to decide on the best time to introduce solids and in particular foods associated with allergies. In the meantime, a lot more research is still required.Debbie Kennetthttps://www.blogger.com/profile/11573470282571579765noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-77115784310264862172011-01-21T17:46:39.339+01:002011-01-21T17:46:39.339+01:00Keith
Thanks for an interesting post. It was a pi...Keith<br /><br />Thanks for an interesting post. It was a pity that the BMJ article, which offered no new evidence and selectively quoted from the literature, received front page headlines in the UK and in The Times too which should have known better! The headlines in some of the newspapers also in some cases completely distorted the facts.<br /><br />There was another interesting article in The Times which you might not have seen about the new EAT study. This might eventually help to answer some of the questions about allergies and the optimum timing for the introduction of solids. The article is behind the Times paywall:<br /><br />http://www.thetimes.co.uk/tto/health/child-health/article2877749.ece<br /><br />There is further information on the EAT study's website here:<br /><br />http://www.eatstudy.co.uk<br /><br />It will be interesting to see if in due course parents will be able to use information from genetic tests to help with decisions such as when to introduce solids. The 23andMe test already includes four markers associated with coeliac disease. I have the low-risk version of the one that is particularly linked with coeliac disease.Debbie Kennetthttps://www.blogger.com/profile/11573470282571579765noreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-48229667407179912502011-01-17T19:30:00.639+01:002011-01-17T19:30:00.639+01:00Have you seen this http://www.analyticalarmadillo....Have you seen this http://www.analyticalarmadillo.co.uk/2011/01/starting-solids-facts-behind-todays.html interesting look at the paper. I cant seem to see a study that looks at exclusivity until 6 months and outcome, it seems to be mixed feeding and gluten LATER than 7 monthsAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-77144012144174341322010-12-17T08:24:34.712+01:002010-12-17T08:24:34.712+01:00Moreno - thanks, usually I agree with you, not thi...Moreno - thanks, usually I agree with you, not this time though. However note that the word is GENius and not ENVius... what does that tell us?<br /><br />Robert, thanks, and I'm sure that whole genome sequencing of populations will explain the strange phenotype of those who think that the environment has any importance at all...Keith Grimaldihttp://eurogene.blogspot.comnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-58278115047977432422010-12-16T23:11:13.641+01:002010-12-16T23:11:13.641+01:00I agree with everything in this post, including th...I agree with everything in this post, including the conclusion. Years of working with budding yeast (and bacteria prior to that; plus stint of fly work) taught me that genetics ordinarily contributes far more to phenotype than environment ever will. IMO most yeast-, fly-, worm-, fish-, and mouse geneticists would agree with that view. The fact that GWAS of common variants hasn't fully explained heritability and pathophysiology of human disease is beyond incredibly narrow-minded, short-sighted, and impatient. And, as hinted at in this post, genetic understanding has proceeded, and will continue to, faster than understanding of potential environmental disrupters ever will.Robert Westhttp://www.upstate.edu/biochem/faculty-rest.php?EmpID=ChAFPxPxnoreply@blogger.comtag:blogger.com,1999:blog-3842803027215900708.post-74763295345437094072010-12-16T15:57:17.678+01:002010-12-16T15:57:17.678+01:00Keith, you are a genius. Now I know for sure.Keith, you are a genius. Now I know for sure.Anonymousnoreply@blogger.com